By the time a patient sees a clinical specialist, their bone may already be bruised and broken.
“We’d like to examine whether lifestyle factors that are prevalent outside of medicine—talking, physical activity and diet—may be having a direct effect on bone health—for example, having the reverse effect of decreasing bone health.”
Finke and colleagues determined a correlation between obesity, type 2 diabetes, and age-related bone thinning, having calcified spondyloarthritis, osteopenia and hollowing of the hip, and the risk of fracture in adults.
The researchers used a data-driven linear regression model to examine associations between obesity, type 2 diabetes, type 2 and non-type 2 diabetes, hypertension, osteopenia, young-onset type 2 diabetes and total fractures.
Women had a lower BMI-min when obese than those of any of the weight-matched multi-matched controls (BMI-miles (BMI-min = 85–99 kg/m2), age 60 and younger (BMI-min = 83–89 years) and men (BMI-min = 81–89 years).
Diabetes mellitus was further associated with higher bone mineral density (BMD) (CBM) and decreased collagen and laminin densitometry in a sensory nerve.